Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.
Human, Mouse, Rat
Cancer, Cell Biology, Metabolism, Neuroscience, Signal Transduction
Store at -20°C. Avoid freeze / thaw cycles.
Recombinant fusion protein of human GSS (NP_000169.1).
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
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