Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.
(KO Validated) GSS Polyclonal Antibody
£288.00 – £580.00 excluding VAT
Size | 120μL, 200μL |
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Swissprot | P48637 |
Applications | WB |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Research Areas | Cancer, Cell Biology, Metabolism, Neuroscience, Signal Transduction |
Concentration | 1 mg/mL |
Storage | Store at -20°C. Avoid freeze / thaw cycles. |
Immunogen | Recombinant fusion protein of human GSS (NP_000169.1). |
Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
Purification Method | Affinity purification |
Dilution | WB 1:500-1:2000 |
Conjugation | Unconjugated |
Clonality | |
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