This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.
(KO Validated) HMGB1 Polyclonal Antibody
£288.00 – £580.00 excluding VAT
| Size | 120μL, 200μL |
|---|---|
| Swissprot | P09429 |
| Applications | WB, IHC, IF |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C. Avoid freeze / thaw cycles. |
| Immunogen | A synthetic peptide of human HMGB1 (NP_002119.1). |
| Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Purification Method | Affinity purification |
| Dilution | WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200 |
| Conjugation | Unconjugated |
| Clonality | |
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