Fagus Antibody Services

(KO Validated) HuR / ELAVL1 Polyclonal Antibody

£288.00£580.00 excluding VAT

SKU FAS-65532-A Category Tags , , , , ,

The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3′ untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.

Size

120μL, 200μL

Swissprot

Q15717

Applications

WB, IHC, IF

Reactivity

Human, Mouse

Host

Rabbit

Isotype

IgG

Research Areas

Cancer, Epigenetics and Nuclear Signaling

Concentration

1 mg/mL

Storage

Store at -20°C. Avoid freeze / thaw cycles.

Immunogen

A synthetic peptide of human HuR / ELAVL1 (NP_001410.2).

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method

Affinity purification

Dilution

WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:200

Conjugation

Unconjugated

Clonality

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