The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3′ untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.
(KO Validated) HuR / ELAVL1 Polyclonal Antibody
£288.00 – £580.00 excluding VAT
Size | 120μL, 200μL |
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Swissprot | Q15717 |
Applications | WB, IHC, IF |
Reactivity | Human, Mouse |
Host | Rabbit |
Isotype | IgG |
Research Areas | Cancer, Epigenetics and Nuclear Signaling |
Concentration | 1 mg/mL |
Storage | Store at -20°C. Avoid freeze / thaw cycles. |
Immunogen | A synthetic peptide of human HuR / ELAVL1 (NP_001410.2). |
Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
Purification Method | Affinity purification |
Dilution | WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:200 |
Conjugation | Unconjugated |
Clonality | |
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