The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
(KO Validated) NDUFS2 Polyclonal Antibody
£288.00 – £580.00 excluding VAT
| Size | 120μL, 200μL |
|---|---|
| Swissprot | O75306 |
| Applications | WB, IF |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Research Areas | Cancer, Cell Biology, Metabolism, Signal Transduction, Tags and Cell Markers |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C. Avoid freeze / thaw cycles. |
| Immunogen | Recombinant fusion protein of human NDUFS2 (NP_004541.1). |
| Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Purification Method | Affinity purification |
| Dilution | WB 1:1000-1:3000 IF 1:50-1:200 |
| Conjugation | Unconjugated |
| Clonality | |
| Citation Link 1 | |
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