Platelet endothelial cell adhesion molecule-1 (PECAM-1,CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. It is highly expressed on the surface of the endothelium,making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets,monocytes,neutrophils,natural killer cells,megakaryocytes and some types of T-cell . As well as its role in cell-cell adhesion,PECAM-1 functions as a signaling receptor,and is involved in important physiological events such as nitric oxide production,regulation of T-cell immunity and tolerance,leukocyte transendothelial migration and inflammation and angiogenesis .
Recombinant CD31 Monoclonal Antibody
£208.00 – £260.00 excluding VAT
| Size | 100μL |
|---|---|
| Swissprot | P16284 |
| Applications | WB, IHC-P |
| Reactivity | Human |
| Host | Rabbit |
| Isotype | IgG |
| Research Areas | Cancer, Cardiovascular, Immunology, Signal Transduction, Stem Cells |
| Concentration | 300 ?g/mL |
| Storage | Store at -20?. Avoid freeze / thaw cycles. |
| Immunogen | |
| Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Purification Method | Affinity Purified |
| Dilution | WB 1:1000-1:5000 IHC 1:20-1:100 |
| Conjugation | Unconjugated |
| Clonality | Rabbit Monoclonal |
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