This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
Recombinant FTO Monoclonal Antibody
£208.00 – £260.00 excluding VAT
| Size | 100μL |
|---|---|
| Swissprot | Q9C0B1 |
| Applications | WB, IHC-P, IF |
| Reactivity | Human |
| Host | Rabbit |
| Isotype | IgG |
| Research Areas | Cancer, Cardiovascular, Metabolism, Neuroscience |
| Concentration | 300 ?g/mL |
| Storage | Store at -20?. Avoid freeze / thaw cycles. |
| Immunogen | |
| Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Purification Method | Affinity Purified |
| Dilution | WB 1:2000-5000 IHC 1:50-1:100 IF 1:20-1:100 |
| Conjugation | Unconjugated |
| Clonality | Rabbit Monoclonal |
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