Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
Recombinant Human CD74 protein (His Tag)
£79.20 – £239.20 excluding VAT
SKU
FAS-500010-P
Category Protein
Tags CD 74, CD74 antigen (invariant polypeptide of major histocompatibility complex, CD74 molecule, class II antigen-associated), class II invariant chain, CLIP, DHLAG, Gamma chain of class II antigens, HG2A, HLA class II histocompatibility antigen gamma chain, HLA DR antigens associated invariant chain, HLA DR gamma, HLA-DR antigens-associated invariant chain, HLA-DR-gamma, HLADG, HLADR antigens associated invariant chain, Ia antigen associated invariant chain, Ia antigen-associated invariant chain, Ia associated invariant chain, Ia gamma, Ii, Invariant polypeptide of major histocompatibility complex class II antigen associated, la-gamma, major histocompatibility complex, Major histocompatibility complex class II invariant chain, MHC HLA DR gamma chain, MHC HLA-DR gamma chain, p33, p35, Protein 41
Size | 20µg, 100µg |
---|---|
Active Protein | Active protein |
Activity | Immunogen(E-AB-40347) |
Protein Construction | A DNA sequence encoding theHuman CD74 protein (P04233) (73Q-296M) was expressed with a polyhistidine tag at the N-terminus. |
Sequence | 73Q-296M |
Fusion Tag | N/C-His |
Accession | P04233 |
Species | Human |
Expressed Host | E.coli |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Purity | > 90 % as determined by reducing SDS-PAGE. |
Endotoxin | Please contact us for more information. |
Stability and Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Mol Mass | 26.6kDa |
AP Mol Mass | 30-33kDa |
Formulation | Lyophilized from sterile PBS, pH 7.4 |
Research Areas | immunology |
Reconstitution | Please refer to the printed manual for detailed information. |