Nectin-2( CD112) is a member of the nectin family, which contains two Ig-like C2-type domains and one Ig-like V-type domain in the extracellular region. Nectins are type I transmembrane glycoproteins that are calcium-independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs). Nectin2 is widely expressed in human tissues including brain, spinal cord, spleen, kidney, heart and liver. It can form trans-heterodimers with PVRL3/nectin-3 and interacts with CD226. Mutations of alleles of the murine CD112 gene can result in conditions such as morphologically aberrant spermatozoa. It may function in allergic reactions, and accordingly may used as a novel target for anti-allergic therapy.
Recombinant Mouse CD112/Nectin-2 Protein (His Tag)(Active)
£49.60 – £142.40 excluding VAT
| Size | 10µg, 50µg |
|---|---|
| Active Protein | Active protein |
| Activity | Immobilized Human DNAM-1-Fc(Cat: PKSH033729) at 2μg/ml(100 μl/well) can bind Human Nectin-2-His. |
| Protein Construction | Recombinant Mouse Poliovirus Receptor-Related Protein 2 is produced by our Mammalian expression system and the target gene encoding Gln32-Gly351 is expressed with a 6His tag at the C-terminus. |
| Sequence | Gln32-Gly351 |
| Fusion Tag | C-6His |
| Accession | NP_033016.3 |
| Species | Mouse |
| Expressed Host | Human Cells |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg as determined by the LAL method. |
| Stability and Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Mol Mass | 35.6 kDa |
| AP Mol Mass | 40-45 kDa |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4. |
| Research Areas | |
| Reconstitution | Please refer to the printed manual for detailed information. |
Related Product
Related products
-
-
-
-
-
-
-
Protein
Recombinant ZIKV (strain Zika SPH2015) NS5 protein (His Tag)
£363.20 – £855.00 excluding VAT -
-
-
Protein
Recombinant SARS-CoV-2 (2019-nCoV) S protein RBD (C-mFc-6His tag)(Active)
£180.00 – £875.00 excluding VAT