The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
CD74 Polyclonal Antibody
£184.00 – £380.00 excluding VAT
| Size | 120μL, 200μL |
|---|---|
| Swissprot | P04233 |
| Applications | WB, IHC |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Research Areas | Cancer, Immunology |
| Concentration | 0.95 mg/mL |
| Storage | Store at -20°C. Avoid freeze / thaw cycles. |
| Immunogen | Recombinant Human HLA class II histocompatibility antigen gamma chain protein |
| Buffer | PBS with 0.05% Proclin300 and 50% glycerol, pH7.4. |
| Purification Method | Antigen Affinity Purification |
| Dilution | WB 1:500-1:1000 IHC 1:100-1:300 |
| Conjugation | Unconjugated |
| Clonality | Polyclonal |
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