The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
(KO Validated) PARK7 Polyclonal Antibody
£288.00 – £580.00 excluding VAT
| Size | 120μL, 200μL |
|---|---|
| Swissprot | Q99497 |
| Applications | WB, IF |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Isotype | IgG |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Metabolism, Neuroscience, Signal Transduction |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C. Avoid freeze / thaw cycles. |
| Immunogen | Recombinant fusion protein of human PARK7 (NP_001116849.1). |
| Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Purification Method | Affinity purification |
| Dilution | WB 1:500-1:2000 IF 1:50-1:200 |
| Conjugation | Unconjugated |
| Clonality | |
| Citation Link 1 | |
| Citation Link 2 | |
| Citation Link 3 | |
| Citation Link 4 | |
| Citation Link 5 |
