Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses.
Recombinant Mouse IL7RA/CD127 Protein (Fc Tag)(Active)
£93.60 – £237.60 excluding VAT
| Size | 10µg, 50µg |
|---|---|
| Active Protein | Active protein |
| Activity | Immobilized Human IL-7-His(Cat: PKSH032654) at 10μg/ml(100 μl/well) can bind Mouse IL-7RA-Fc. |
| Protein Construction | Recombinant Mouse Interleukin-7 receptor subunit alpha is produced by our Mammalian expression system and the target gene encoding Glu21-Asp239 is expressed with a Fc tag at the C-terminus. |
| Sequence | Glu21-Asp239 |
| Fusion Tag | C-Fc |
| Accession | NP_032398.3 |
| Species | Mouse |
| Expressed Host | Human Cells |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg as determined by the LAL method. |
| Stability and Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Mol Mass | 52.1 kDa |
| AP Mol Mass | 61-75 kDa |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Research Areas | |
| Reconstitution | Please refer to the printed manual for detailed information. |
