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Recombinant Mouse CCL8/MCP-2 Protein (His Tag)

£142.40 – £418.40 excluding VAT

SKU FAS-040983-P Category Tag

Chemokine ligand 8 (CCL8,MCP-2), is a small secreted cytokine which belongs to the intercrine beta (chemokine CC) family. CCL8 Chemotactic factor attracts monocytes. It can bind heparin.CCL8 functions to activate different immune cells, including mast cells, eosinophils and basophils which are involved in allergic responses, monocytes, and T cells and NK cells which are involved in the inflammatory response. Its ability achieves by binding to different cell surface receptors termed chemokine receptors including CCR1, CCR2B and CCR5. It has been reported that CCL8 is a potent inhibitor of HIV-1 by virtue of its binding to CCR5 which is one of the major co-receptors for HIV-1.

Size

10µg, 50µg
Active Protein
Activity
Protein Construction

Recombinant Mouse C-C motif Chemokine 8 is produced by our Mammalian expression system and the target gene encoding Glu20-Pro97 is expressed with a 6His tag at the C-terminus.
Sequence

Glu20-Pro97
Fusion Tag

C-6His
Accession

Q9Z121
Species

Mouse
Expressed Host

Human Cells
Shipping

This product is provided as lyophilized powder which is shipped with ice packs.
Purity

> 95 % as determined by reducing SDS-PAGE.
Endotoxin

< 1.0 EU per μg as determined by the LAL method.
Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Mol Mass

9.8 kDa
AP Mol Mass

12 kDa
Formulation

Lyophilized from a 0.2 μm filtered solution of 20mM Hac-NaC, 150mM NaCl, pH4.0.
Research Areas
Reconstitution

Please refer to the printed manual for detailed information.

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