Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1.
Recombinant Mouse Galectin 9/LGALS9 Protein (GST Tag)
£196.00 – £329.60 excluding VAT
| Size | 10µg, 50µg |
|---|---|
| Active Protein | |
| Activity | |
| Protein Construction | Recombinant Mouse Galectin-9 is produced by our E.coli expression system and the target gene encoding Met1-Thr322 is expressed with a GST tag at the N-terminus. |
| Sequence | Met1-Thr322 |
| Fusion Tag | N-GST |
| Accession | O08573-2 |
| Species | Mouse |
| Expressed Host | E.coli |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C. |
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg as determined by the LAL method. |
| Stability and Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Mol Mass | 62.8 kDa |
| AP Mol Mass | 58 kDa |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM PB, 1mM EDTA, 5mM p-ME, 5%Trehalose, 400mM Nacl, pH6.5 |
| Research Areas | |
| Reconstitution | Not Applicable |
