TLR4,also named as CD284,belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88,TIRAP and TRAF6,leading to NF-kappa-B activation,cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
CD284 Monoclonal Antibody
£192.00 – £399.00 excluding VAT
| Size | 120μL, 200μL |
|---|---|
| Swissprot | Q9QUK6, Q9QX05 |
| Applications | IHC |
| Reactivity | Mouse, Rat |
| Host | Mouse |
| Isotype | IgG |
| Research Areas | Cancer, Cardiovascular, Immunology, Microbiology |
| Concentration | 1.8 mg/mL |
| Storage | Store at -20°C. Avoid freeze / thaw cycles. |
| Immunogen | Recombinant protein corresponding to Mouse TLR4 |
| Buffer | PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4 |
| Purification Method | Affinity purification |
| Dilution | IHC 1:200-1:800 |
| Conjugation | Unconjugated |
| Clonality | Monoclonal |
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