Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Histone H3 Monoclonal Antibody
£192.00 – £319.20 excluding VAT
| Size | 120μL, 200μL |
|---|---|
| Swissprot | P68431, Q71DI3, P84243 |
| Applications | IF, IHC-p, IP, WB |
| Reactivity | Human 1, Mouse, Rat, Yeast |
| Host | Mouse |
| Isotype | IgG |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C. Avoid freeze / thaw cycles. |
| Immunogen | Recombinant Protein |
| Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
| Purification Method | Protein A purification |
| Dilution | WB 1:500-1:2000, IHC 1:50-300, IF 1:100-500, IP 1:100-1:300 |
| Conjugation | Unconjugated |
| Clonality | Monoclonal |
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