From: £205.60
Anterior gradient protein 3 (AGR3) is an 18 kDa member of the AGR family of proteins. It is expressed in the ciliated cells of the airway epithelium, not detected in the mucous cells. Mature human AGR3 shares 92% amino acid sequence identity with mouse AGR3. It is required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. AGR3 might be involved in the regulation of intracellular calcium in tracheal epithelial cells.
| Size | 10µg, 50µg |
|---|---|
| Active Protein | |
| Activity | |
| Protein Construction | Recombinant Mouse AGR3 is produced by our Mammalian expression system and the target gene encoding Ile21-Leu165 is expressed with a 6His tag at the C-terminus. |
| Sequence | Ile21-Leu165 |
| Fusion Tag | C-His |
| Accession | Q8R3W7 |
| Species | Mouse |
| Expressed Host | Human Cells |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C. |
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg as determined by the LAL method. |
| Stability and Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Mol Mass | 18.1 kDa |
| AP Mol Mass | 16 kDa |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris, 10%Glycerol, 100mM NaCl, pH8.0. |
| Research Areas | |
| Reconstitution | Not Applicable |
