Anterior gradient protein 3 (AGR3) is an 18 kDa member of the AGR family of proteins. It is expressed in the ciliated cells of the airway epithelium, not detected in the mucous cells. Mature human AGR3 shares 92% amino acid sequence identity with mouse AGR3. It is required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. AGR3 might be involved in the regulation of intracellular calcium in tracheal epithelial cells.
Recombinant Mouse AGR3 Protein (His Tag)
£205.60 – £357.60 excluding VAT
| Size | 10µg, 50µg |
|---|---|
| Active Protein | |
| Activity | |
| Protein Construction | Recombinant Mouse AGR3 is produced by our Mammalian expression system and the target gene encoding Ile21-Leu165 is expressed with a 6His tag at the C-terminus. |
| Sequence | Ile21-Leu165 |
| Fusion Tag | C-His |
| Accession | Q8R3W7 |
| Species | Mouse |
| Expressed Host | Human Cells |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C. |
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg as determined by the LAL method. |
| Stability and Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Mol Mass | 18.1 kDa |
| AP Mol Mass | 16 kDa |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris, 10%Glycerol, 100mM NaCl, pH8.0. |
| Research Areas | |
| Reconstitution | Not Applicable |
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