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Recombinant Mouse Carbonic Anhydrase 4/CA4 Protein (aa 18-277, His Tag)

£178.40 – £474.40 excluding VAT

SKU FAS-040973-P Category Tag

Carbonic anhydrase 4(CA4) is an enzyme that belongs to the alpha-carbonic anhydrase family. CA4 consists of a signal peptide (residues1-17), an ectodomain (residues18-277) and a propeptide (residues278-305), which is removed in the mature form. it is predominantly expressed in the embryo. CA4 can catalyzes the reversible reaction of CO2+H2O=HCO3-+H+, and stimulates the sodium/bicarbonate transporter activity of SLC4A4. Studies have shown that this protein have a role in inherited renal abnormalities of bicarbonate transport. Alpha-carbonic anhydrase family participate in avariety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor. They show extensive diversity in tissue is attribution and in their sub cellular localization.

Size

10µg, 50µg
Active Protein
Activity
Protein Construction

Recombinant Mouse Carbonic anhydrase 4 is produced by our Mammalian expression system and the target gene encoding Glu18-Ser277 is expressed with a 6His tag at the C-terminus.
Sequence

Glu18-Ser277
Fusion Tag

C-6His
Accession

Q64444
Species

Mouse
Expressed Host

Human Cells
Shipping

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity

> 95 % as determined by reducing SDS-PAGE.
Endotoxin

< 1.0 EU per μg as determined by the LAL method.
Stability and Storage

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Mol Mass

30.5 kDa
AP Mol Mass

36kDa
Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH8.0.
Research Areas
Reconstitution

Not Applicable

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